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Gastric Variceal Glue Injection

Gastric Variceal Glue Injection is a specialized endoscopic treatment used to manage gastric varices—abnormally enlarged veins in the stomach that develop due to portal hypertension, often a result of liver cirrhosis. These varices are prone to sudden, severe bleeding, which can be life-threatening if not treated promptly.

What Are Gastric Varices?

Gastric varices are dilated veins that form in the stomach when blood flow through the liver is obstructed, causing increased pressure in the portal venous system. Compared to esophageal varices, gastric varices are less common but more difficult to treat and tend to bleed more profusely when they rupture.

    What Is Glue Injection?

    In this procedure, a special medical adhesive—usually N-butyl cyanoacrylate—is injected directly into the bleeding varix via an endoscope. This "glue" hardens rapidly, effectively sealing the vein and stopping the bleeding.

      How the Procedure Works:
      • A gastroscope (a thin, flexible tube with a camera) is passed through the mouth into the stomach.
      • The bleeding varix is identified.
      • A small amount of glue mixed with lipiodol (radiopaque dye) is injected into the varix.
      • The glue solidifies immediately, blocking blood flow and achieving hemostasis.
      When Is It Recommended?
      • Active bleeding from gastric varices
      • High-risk gastric varices identified during endoscopy
      • As a life-saving emergency treatment or preventive therapy in cirrhotic patients
      Benefits of Gastric Variceal Glue Injection:
      • Immediate control of active bleeding
      • Minimally invasive, non-surgical solution
      • Can be life-saving in emergency situations
      • Helps prevent recurrent bleeding episodes
      Is It Safe?

      Yes, the procedure is effective and relatively safe when performed by experienced gastroenterologists. However, potential risks include:

      • Rebleeding (may need repeat injection)
      • Glue migration to other areas like the lungs (very rare)
      • Minor ulceration or discomfort at the injection site

      Patients are typically monitored closely after the procedure and may require follow-up endoscopy or additional treatments depending on the severity of their liver disease.

      Gastric Variceal Glue Injection is a critical intervention in managing bleeding complications of advanced liver disease, offering rapid and effective control in high-risk patients.